The performance of passive safety devices to protect vulnerable road users, or otherwise endangered persons,
from severe injuries in cases of impacts and accidents has improved notably in recent decades. The devices’
levels of performance appear to have plateaued but the numbers of severe injuries and deaths caused in such
incidents could be decreased further if new solutions are found. At first, the possibilities for improving the
impact behavior of passive safety devices may appear to be restricted to device geometry; however, it is in fact
also possible to rethink the applied materials and to utilize natural principles in their design. In this study, impact
related brain injury mechanisms and injury criteria are investigated using dynamic simulations and Finite
Element Head Models, results from which are compared with data collected from real-life accidents. As these
tools are advancing considerably in terms of accuracy, information density and complexity, they provide, like
expert knowledge from the fields of biomechanics, biomedicine and neuroscience, valuable input for further
development.